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Open problems in Image segmentation

Lack of benchmarks for real-world clinical deployment1 paper raises it · 0 address it
Current benchmarks do not reflect how clinicians actually use AI systems, limiting their predictive value for real-world performance.
- Clinician use of language models diverges from how the models are evaluatedraises
Handling gigapixel whole-slide images in segmentation1 paper raises it · 1 addresses it
Existing models operate at patch scale, but clinical supervision and labels are at the whole-slide level, creating a mismatch.
- BigCell: Generating Gigapixel Whole-Slide Imagesraises · addresses
Temporal modeling of multimodal clinical trajectories1 paper raises it · 1 addresses it
Accurate risk prediction requires modeling irregular, heterogeneous clinical data over time, which current approaches often overlook.
- TRACE: Tracking Multimodal Clinical Trajectories for Inpatient Risk Predictionraises · addresses
Resistance to incidental information in clinical reasoning1 paper raises it · 0 address it
Models may misattribute or be distracted by irrelevant information in clinical documentation, leading to errors.
- Large language models are vulnerable to incidental information in clinical documentation and reasoningraises
Learning from deployment experience without retraining1 paper raises it · 1 addresses it
Frozen models cannot adapt to new clinical evidence or updated guidelines without access to weights or additional training.
- Frozen Models, Evolving Expertise: Model-Agnostic Learning from Deployment Experience for Multimodal Medical AIraises · addresses

Named by an AI from these papers' abstracts.

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Topics in this field

image segmentation · volumetric · medical image409 papers40 this week
radiology report generation · medical vision language · vision language models133 papers35 this week
clinical reasoning · question answering · language models210 papers21 this week
eeg foundation models · electroencephalography eeg · eeg foundation158 papers19 this week
patient history · clinical data · health records112 papers19 this week
electrocardiogram ecg · electrocardiogram · ecgs147 papers13 this week

Topics in this field

Active contributors · 90 days

Active contributors

Activity · 12 weeks

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All papers in Research

arXiv cs.LGSep 24
GeoACE: Geometry-Diverse Anchor-Correction Ensembles for Heterogeneous Treatment Effect Estimation
Ali Haghpanah Jahromi, Mohammad Taheri, Zohreh Azimifar
Predicting heterogeneous causal effects supports informed decision-making, yet suitable inductive biases vary with treatment overlap, covariate imbalance, prognostic structure, and sample size. The Geometry-Diverse Anchor--Correction Expert Ensemble (GeoACE) addresses this variation through five complementary experts whose predictions are combined using weights estimated from validation data. Compared with ensemble designs that derive diversity primarily from sample or feature subsets, reweighting, or feature transformations, its central contribution is the coordinated design of training objectives and anchor geometries that target different prognostic and overlap structures. Following validation, each expert is refitted on the combined training and validation data, while retaining its distinctive structure. The shared architecture couples a structured outcome anchor with a learned neural correction. ACE serves as the reference estimator, while OW-ACE emphasizes well-supported covariate regions through overlap-weighted factual training. G$Φ$-ACE constructs a global outcome-guided geometry from pooled prognostic associations, whereas A$Φ$-ACE incorporates arm-specific outcome…
PDF arXiv
arXiv cs.LGSep 24
Error- and Prediction-Driven Motor Learning in the Cortico-Cerebellar Loop
Ana Carolina Filipe, Rui Ponte Costa, Cláudia Soares
Robust control under delayed sensory feedback remains a key challenge in both robotics and neuroscience. Classical cerebellar models explain delay compensation through forward prediction but fail to account for fast online corrections and rapid adaptation observed in biological systems. We propose a cerebellum-inspired control framework that combines multiplexed predictive representations with internal feedback. By jointly encoding kinematic variables and task-relevant error signals, the model enables accurate online correction despite delayed feedback. Furthermore, incorporating feedback within the cerebellar loop significantly accelerates adaptation, reducing learning time by an order of magnitude. Our results show that single-signal predictions are insufficient under delay, while multiplexing and feedback together provide a unified mechanism for online control and rapid learning.
PDF arXiv
arXiv cs.LGSep 24
When Temporal Perturbations Act Like Sensor Biases: Label-Free Auditing of Wearable Activity Recognizers
Qingyu Wu, Yuan Wei, Renju Liu, Hua Cheng
Wearable human-activity recognition (HAR) models operate across sensors, subjects, and backbones, yet a smooth waveform may appear temporal while exploiting a persistent sensor offset primarily. We introduce SpectrumAudit, a label-sealed audit that fits a phase-randomized full-window stimulus on calibration windows from subjects held out from training and testing. After selection, it replays its exact DC projection and budget-constrained zero-mean residual on the same frozen victim without refitting. Across 27 victims from three datasets and three backbones, the selected waveforms cause 2.87-40.83-point three-phase robust accuracy losses. Under this replay budget, DC is more damaging than AC on 24/27 victims and recovers at least 90% of the full drop on 22/27; all 5 failures occur on WISDM. In a held-out UTD-MHAD check, the selected waveform causes 13.49-pp accuracy and 11.68-pp macro-F1 losses, versus -0.66 pp for matched random changes. The audit diagnoses offset versus zero-mean variation under a common peak-budget cap. The code will be released upon acceptance.
PDF arXiv
arXiv cs.CGSep 24
It's the Geometry, Not the Model: Effective Rank and Subspace Alignment in Functional Connectivity Classification
Xiao Fan, Jingyuan Li, Yubo Han, Hongbin Guo, Guanya Li +4
Resting-state functional connectivity (FC) is widely used to classify brain phenotypes and disorders. Most pipelines use the full connectome and seek gains through model design. We instead examine how FC geometry constrains classification and cross-site transfer. Across-subject FC variation concentrates in a small effective subspace, suggesting substantial redundancy in nominal dimensions. Across cohorts, these subspaces may differ in orientation even when their effective ranks are comparable, potentially limiting transfer. Across 2,330 subjects from HCP, ABIDE, and ADHD-200, effective-rank analysis reveals strong spectral concentration. Projection onto leading components at the effective-rank scale recovers most of the full-FC classification performance. In ABIDE, site-specific effective subspaces are weakly aligned, and their principal-angle overlap predicts pairwise transfer after covariate adjustment despite comparable per-site effective ranks. Controlled rotations that alter subspace orientation while preserving the mean and covariance spectrum drive transfer toward chance, whereas displacement-matched label-orthogonal rotations do not. These results identify subspace…
PDF arXiv
arXiv cs.LGSep 24
Improving Calibration of Black-Box Radiology AI Using Test-Time Augmentation
Nathan Le, Magdalini Paschali, Arogya Koirala, Andrew Johnston, Zhongnan Fang +3
Radiology AI systems increasingly inform clinical decisions such as triage, follow-up imaging, and treatment planning. For these decisions to be made safely, model outputs must be well calibrated, meaning predicted probabilities accurately reflect true risk. Many standard techniques for improving calibration, such as MC Dropout and Deep Ensembles, require access to model parameters or retraining. However, proprietary clinical AI systems operate as black boxes, preventing access to the model's internals. To that end, we propose a model-agnostic framework for improving calibration of black-box models using clinically grounded test-time augmentation (TTA). Our framework applies geometric and physics-inspired 3D CT perturbations and learns probability-level aggregation strategies without access to model internals or the original training data. Across pulmonary embolism and intracranial hemorrhage detection tasks, DualTTA achieved the strongest overall calibration among TTA methods, reducing the Expected Calibration Error by 54% (0.239 -> 0.109) and 43% (0.051 -> 0.029), respectively, while requiring only input-output access. Additionally, DualTTA outperformed uncertainty estimation…
PDF arXiv
arXiv cs.CVSep 24
EndoFSA: Endoscopic Few-Shot Image Generation via Rank-Constrained Parameter Adaptation
Panagiota Gatoula, Grigoris Karypidis, Dimitris K. Iakovidis
WCE produces large-scale gastrointestinal image data yet pathological findings remain significantly underrepresented limiting the generalization performance of deep-learning based abnormality detection systems. SDG methods offer a practical solution to mitigate this imbalance. However their training directly on scarce abnormal samples often results in instability overfitting and structural distortions. Addressing these challenges requires controlled adaptation mechanisms that preserve anatomical priors while enabling realistic pathological variation. This paper presents EndoFSA a GAN-based model for Endoscopic Few-Shot image generation by Adaptation in WCE imaging. EndoFSA leverages a generator pretrained on abundant normal data and adapts it to abnormal domains using limited number of training samples through a rank-constrained parameter adaptation where only a small number of modulation parameters is updated while the pretrained weights remain frozen. By restricting parameter updates to a low dimensional subspace and incorporating perceptual boundary regularization and cluster-wise diversity control EndoFSA enables efficient model adaptation under limited data conditions and…
PDF arXiv

Papers

Topics in this field

image segmentation · volumetric · medical image409 papers40 this week
radiology report generation · medical vision language · vision language models133 papers35 this week
clinical reasoning · question answering · language models210 papers21 this week
eeg foundation models · electroencephalography eeg · eeg foundation158 papers19 this week
patient history · clinical data · health records112 papers19 this week
electrocardiogram ecg · electrocardiogram · ecgs147 papers13 this week

Active contributors · 90 days

Recent papers

All papers in Research

arXiv cs.LGSep 24
GeoACE: Geometry-Diverse Anchor-Correction Ensembles for Heterogeneous Treatment Effect Estimation
Ali Haghpanah Jahromi, Mohammad Taheri, Zohreh Azimifar
Predicting heterogeneous causal effects supports informed decision-making, yet suitable inductive biases vary with treatment overlap, covariate imbalance, prognostic structure, and sample size. The Geometry-Diverse Anchor--Correction Expert Ensemble (GeoACE) addresses this variation through five complementary experts whose predictions are combined using weights estimated from validation data. Compared with ensemble designs that derive diversity primarily from sample or feature subsets, reweighting, or feature transformations, its central contribution is the coordinated design of training objectives and anchor geometries that target different prognostic and overlap structures. Following validation, each expert is refitted on the combined training and validation data, while retaining its distinctive structure. The shared architecture couples a structured outcome anchor with a learned neural correction. ACE serves as the reference estimator, while OW-ACE emphasizes well-supported covariate regions through overlap-weighted factual training. G$Φ$-ACE constructs a global outcome-guided geometry from pooled prognostic associations, whereas A$Φ$-ACE incorporates arm-specific outcome…
PDF arXiv
arXiv cs.LGSep 24
Error- and Prediction-Driven Motor Learning in the Cortico-Cerebellar Loop
Ana Carolina Filipe, Rui Ponte Costa, Cláudia Soares
Robust control under delayed sensory feedback remains a key challenge in both robotics and neuroscience. Classical cerebellar models explain delay compensation through forward prediction but fail to account for fast online corrections and rapid adaptation observed in biological systems. We propose a cerebellum-inspired control framework that combines multiplexed predictive representations with internal feedback. By jointly encoding kinematic variables and task-relevant error signals, the model enables accurate online correction despite delayed feedback. Furthermore, incorporating feedback within the cerebellar loop significantly accelerates adaptation, reducing learning time by an order of magnitude. Our results show that single-signal predictions are insufficient under delay, while multiplexing and feedback together provide a unified mechanism for online control and rapid learning.
PDF arXiv
arXiv cs.LGSep 24
When Temporal Perturbations Act Like Sensor Biases: Label-Free Auditing of Wearable Activity Recognizers
Qingyu Wu, Yuan Wei, Renju Liu, Hua Cheng
Wearable human-activity recognition (HAR) models operate across sensors, subjects, and backbones, yet a smooth waveform may appear temporal while exploiting a persistent sensor offset primarily. We introduce SpectrumAudit, a label-sealed audit that fits a phase-randomized full-window stimulus on calibration windows from subjects held out from training and testing. After selection, it replays its exact DC projection and budget-constrained zero-mean residual on the same frozen victim without refitting. Across 27 victims from three datasets and three backbones, the selected waveforms cause 2.87-40.83-point three-phase robust accuracy losses. Under this replay budget, DC is more damaging than AC on 24/27 victims and recovers at least 90% of the full drop on 22/27; all 5 failures occur on WISDM. In a held-out UTD-MHAD check, the selected waveform causes 13.49-pp accuracy and 11.68-pp macro-F1 losses, versus -0.66 pp for matched random changes. The audit diagnoses offset versus zero-mean variation under a common peak-budget cap. The code will be released upon acceptance.
PDF arXiv
arXiv cs.CGSep 24
It's the Geometry, Not the Model: Effective Rank and Subspace Alignment in Functional Connectivity Classification
Xiao Fan, Jingyuan Li, Yubo Han, Hongbin Guo, Guanya Li +4
Resting-state functional connectivity (FC) is widely used to classify brain phenotypes and disorders. Most pipelines use the full connectome and seek gains through model design. We instead examine how FC geometry constrains classification and cross-site transfer. Across-subject FC variation concentrates in a small effective subspace, suggesting substantial redundancy in nominal dimensions. Across cohorts, these subspaces may differ in orientation even when their effective ranks are comparable, potentially limiting transfer. Across 2,330 subjects from HCP, ABIDE, and ADHD-200, effective-rank analysis reveals strong spectral concentration. Projection onto leading components at the effective-rank scale recovers most of the full-FC classification performance. In ABIDE, site-specific effective subspaces are weakly aligned, and their principal-angle overlap predicts pairwise transfer after covariate adjustment despite comparable per-site effective ranks. Controlled rotations that alter subspace orientation while preserving the mean and covariance spectrum drive transfer toward chance, whereas displacement-matched label-orthogonal rotations do not. These results identify subspace…
PDF arXiv
arXiv cs.LGSep 24
Improving Calibration of Black-Box Radiology AI Using Test-Time Augmentation
Nathan Le, Magdalini Paschali, Arogya Koirala, Andrew Johnston, Zhongnan Fang +3
Radiology AI systems increasingly inform clinical decisions such as triage, follow-up imaging, and treatment planning. For these decisions to be made safely, model outputs must be well calibrated, meaning predicted probabilities accurately reflect true risk. Many standard techniques for improving calibration, such as MC Dropout and Deep Ensembles, require access to model parameters or retraining. However, proprietary clinical AI systems operate as black boxes, preventing access to the model's internals. To that end, we propose a model-agnostic framework for improving calibration of black-box models using clinically grounded test-time augmentation (TTA). Our framework applies geometric and physics-inspired 3D CT perturbations and learns probability-level aggregation strategies without access to model internals or the original training data. Across pulmonary embolism and intracranial hemorrhage detection tasks, DualTTA achieved the strongest overall calibration among TTA methods, reducing the Expected Calibration Error by 54% (0.239 -> 0.109) and 43% (0.051 -> 0.029), respectively, while requiring only input-output access. Additionally, DualTTA outperformed uncertainty estimation…
PDF arXiv
arXiv cs.CVSep 24
EndoFSA: Endoscopic Few-Shot Image Generation via Rank-Constrained Parameter Adaptation
Panagiota Gatoula, Grigoris Karypidis, Dimitris K. Iakovidis
WCE produces large-scale gastrointestinal image data yet pathological findings remain significantly underrepresented limiting the generalization performance of deep-learning based abnormality detection systems. SDG methods offer a practical solution to mitigate this imbalance. However their training directly on scarce abnormal samples often results in instability overfitting and structural distortions. Addressing these challenges requires controlled adaptation mechanisms that preserve anatomical priors while enabling realistic pathological variation. This paper presents EndoFSA a GAN-based model for Endoscopic Few-Shot image generation by Adaptation in WCE imaging. EndoFSA leverages a generator pretrained on abundant normal data and adapts it to abnormal domains using limited number of training samples through a rank-constrained parameter adaptation where only a small number of modulation parameters is updated while the pretrained weights remain frozen. By restricting parameter updates to a low dimensional subspace and incorporating perceptual boundary regularization and cluster-wise diversity control EndoFSA enables efficient model adaptation under limited data conditions and…
PDF arXiv

Activity · 12 weeks

Fields · AI · updated just now ago

Image segmentation

Found by the topic model: image segmentation, clinical reasoning, eeg foundation models.

147papers this week−29.7% vs last week

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952 papers this month

Open problems in Image segmentation

Lack of benchmarks for real-world clinical deployment1 paper raises it · 0 address it
Current benchmarks do not reflect how clinicians actually use AI systems, limiting their predictive value for real-world performance.
- Clinician use of language models diverges from how the models are evaluatedraises
Handling gigapixel whole-slide images in segmentation1 paper raises it · 1 addresses it
Existing models operate at patch scale, but clinical supervision and labels are at the whole-slide level, creating a mismatch.
- BigCell: Generating Gigapixel Whole-Slide Imagesraises · addresses
Temporal modeling of multimodal clinical trajectories1 paper raises it · 1 addresses it
Accurate risk prediction requires modeling irregular, heterogeneous clinical data over time, which current approaches often overlook.
- TRACE: Tracking Multimodal Clinical Trajectories for Inpatient Risk Predictionraises · addresses
Resistance to incidental information in clinical reasoning1 paper raises it · 0 address it
Models may misattribute or be distracted by irrelevant information in clinical documentation, leading to errors.
- Large language models are vulnerable to incidental information in clinical documentation and reasoningraises
Learning from deployment experience without retraining1 paper raises it · 1 addresses it
Frozen models cannot adapt to new clinical evidence or updated guidelines without access to weights or additional training.
- Frozen Models, Evolving Expertise: Model-Agnostic Learning from Deployment Experience for Multimodal Medical AIraises · addresses

Named by an AI from these papers' abstracts.