ConPro: Contrast Projection Pretraining for Label-Efficient Vessel Segmentation in DSA Sequences

Xinge Guo, Yuanhao Wang, Liqi Shu, Yang Liu, Min Xu

Dense vessel annotation in digital subtraction angiography (DSA) is labor-intensive, yet every unlabeled sequence records how contrast passes through the vessels. Semi-supervised methods take their targets from the current model, and generic self-supervised pretexts reconstruct static appearance, so this signal goes unused. We propose ConPro, a self-supervised pretraining scheme whose target is a contrast projection, the normalized drop of every pixel below its temporal median over the sequence. On DIAS and DSCA, with 10%, 20% and 50% of the training cases labeled, ConPro improves on training from scratch at every label fraction and is the best of the compared methods on DSCA at 20% and 50% labels. Controlled comparisons show that the gain comes from the target. A temporal-median target with the same input, loss and budget stays at scratch level, and using the projection directly instead of learning it, as an input channel or a pseudo-label, helps little or hurts. ConPro provides pretrained weights without changing the segmentation architecture, so it combines with semi-supervised training, and UniMatch, the strongest baseline, gains 0.5 to 2.0 Dice and 0.9 to 2.3 clDice at every…