High-Capacity Robust Medical Image Exfiltration via Neural Network Weight Replacement

Elie Thellier, Huiyu Li, Nicholas Ayache, Hervé Delingette

Collaborative medical AI platforms allow researchers to train models on sensitive imaging data while restricting data export. However, trained models can serve as covert carriers of patient information: medical images may be encoded within model parameters and reconstructed outside the secure environment. Existing defenses rely on lightweight sanitization (e.g., fine-tuning, pruning, quantization) and limited statistical auditing, creating a realistic insider exfiltration risk. We introduce a high-capacity neural steganography attack that encodes medical images as continuous latent representations embedded into model initialization. A StyleGAN2-based adversarial autoencoder learns compact latent codes regularized to match standard weight initialization statistics, keeping embedded parameters statistically consistent with clean models. Noise injection during training improves robustness to export-time mitigation. The carrier model remains functional on its intended task and hidden images can be reconstructed directly from its weights after export. This continuous encoding enables robust and scalable exfiltration, allowing up to 99 brain MRI volumes to be embedded within a 30MB…