QuPID: Quantum Parameter-Efficient Input-Dependent Retrieval Adaptation for Medical RAG

Hyojun Ahn, Emily Jimin Roh, Soohyun Park, Walid Saad, Hyung-Chul Lee +1

Fidelity-based quantum retrieval ranks candidates by the fidelity between query and archive states. Applying a shared input-independent unitary after fixed state encoding leaves that fidelity unchanged, so training the circuit cannot alter the ranking. Quantum parameter-efficient input-dependent retrieval adaptation (QuPID) repairs this by making the circuit input-dependent through data re-uploading and by comparing measurement readouts, vectors of local Pauli expectations, rather than states. The result is a small readout for adapting frozen image features to a local archive with limited data: training simulates the circuit classically, and inference runs on a GPU with fixed learned parameters. We characterize the class as a structured factorization of input-modulated quadratic feature maps, bound the frequency support of its re-uploading channel, and give a parameter-count generalization bound that motivates its small budget. Under a shared frozen backbone and a label-free protocol, QuPID's 60 parameters give higher precision-at-5 (P@5) on ChestX-ray14 and MURA than frozen medical encoders, and than adapters and low-rank adaptation (LoRA) with up to 5.25 million trainable…