Research-Native by Construction: Minimal Nodes, Re-verifiable Workflows, and Compounding Memory for Long-Horizon Scientific Agents

Di Wang, Yu Liu, Bing Cui, Chaoqun Ji, Dongyuan Ni +3

We describe AfS (Agent for Science), a platform built for long-horizon scientific work, where a project runs for tens of hours across dozens of agent runs with a human present only occasionally. Most agents for science are general coding agents with a skills folder attached, and they inherit that lineage's failure mode: under pressure to finish, they fabricate, skip, or smooth over. Our design rests on one claim: most of the credibility of machine-made research can be moved from asking the model to behave to making the non-compliant state unrepresentable. We encode research discipline as mechanically enforced laws (commitment before measurement; unforgeable freezing; reports are not facts; evidence persists but verdicts do not; negative results are first-class; mechanical questions to the framework and semantic judgment to the model), organized around three time horizons: a minimal set of research nodes within a run, an inquiry contract with frozen closure conditions and a hash-chained artifact ledger within a project, and a two-tier knowledge base with promotion by rewriting across projects. This is a system description written under one rule: each mechanism appears in exactly…