Re-ranking and Late Interaction Drive Retrieval Quality: A Controlled Comparison of RAG Strategies for Scientific Question Answering

Bhagyesh Rathi, Eshan Chawla, William B. Andreopoulos

Retrieval-Augmented Generation (RAG) is now the standard way to ground Large Language Models (LLMs) in external knowledge, yet the design space of retrieval pipelines is large and the trade-offs between variants are not well understood, especially on domain-specific corpora at realistic scale. In this work, we present a controlled comparison of six retrieval strategies for scientific question answering: (i) classic top-k dense retrieval, (ii) LLM-based query rephrasing, (iii) query rephrasing followed by LLM-based reranking, (iv) multi-query fusion via Reciprocal Rank Fusion (RRF), (v) an agentic tool-call pipeline in which the generator decides for itself whether to retrieve, and (vi) late-interaction retrieval with ColBERTv2. All six pipelines share the same generator (Meta-Llama/Llama-3.1-8B-Instruct), prompt, and evaluation protocol; the five single-vector pipelines additionally share SPECTER2 embeddings and a Chroma vector store; and all six retrieve from the full corpus of 463,971 arXiv papers dated 2024-2025. To support reproducible, large-scale evaluation, we also release a synthetic question dataset of 19,484 problem-statement and methodology questions generated by…