Ontology Concept Overlap as a Training Signal: Knowledge-Grounded Reinforcement Learning for Clinical Question Answering

Aditya Tanna, Abhishek Jindal

Reinforcement learning post-training for language models relies on two reward designs: human preferences (RLHF, DPO) and binary verifiers (RLVR). Clinical question answering fits neither. Near-correct answers differ by a single substituted entity, and no executable check decides clinical correctness. We instantiate a soft verifier from a maintained controlled vocabulary: UMLS Concept Unique Identifier overlap (via scispaCy, set-level F1) gives a graded, externally specified reward computed without a model in the loop. We combine it inside GRPO with an entropy-normalised LLM judge, which covers the safety and evidence axes overlap cannot see, and a small consistency penalty on padding and repetition that keeps early-training samples scorable. This three-term composite improves over SFT on Phi-3-mini (3.8B) over MedQA by 2.9% on EM (0.700 vs 0.680) and 39% on Token-F1 (0.202 vs 0.145); on Llama-3.2-3B the corresponding gains are 14% on EM and 35% on Token-F1. We report Token-F1 as the primary metric because it credits partially-correct clinical content that EM discards at this open-generation scale. Main-table results are means over 3 seeds with standard deviations below 0.005. The…