Data Fusion for Errors-in-Variables

Huali Zhao, Molei Liu, Tianying Wang

We study errors-in-variables problems in which a target study contains only a single error-prone surrogate of an unobserved exposure, while an external source study provides repeated surrogate measurements from a different population. The measurement error distribution is allowed to depend on the observed error-free variables, and the error-free variable distribution itself may differ between studies. We introduce a conditional transportability assumption that enables the use of external repeated measurements under source-target heterogeneity. Together with additional replicate-error conditions, it identifies the target conditional measurement-error distribution. Building on this identification result, we develop a data-fusion estimator for a broad class of target functionals. The estimator combines conditional deconvolution, flexible nuisance estimation, and orthogonal correction that reduces first-order sensitivity to nuisance estimation. For the proposed estimator, we develop a unified spectral theory covering both diffuse-spectrum and finite atomic-spectrum target functionals, derive a general asymptotic expansion, and establish consistency and target-specific…