AD-GS: Anatomical Density-guided 3D Gaussian Splatting for Sparse-View Dental CBCT Reconstruction

Zonglin Li, Kexian Xie, Feiran Li, Chu Zhou, Yixing Huang +3

Sparse-view Cone-Beam Computed Tomography (CBCT) reconstruction is essential for reducing radiation dose and scan effort, but remains underconstrained due to limited projection information. Recent 3D Gaussian Splatting (3DGS)-based CBCT reconstruction methods rely on gradient-driven densification, which becomes unstable under sparse acquisition and often leads to over-smoothed structures. We propose AD-GS, an Anatomical Density-guided 3D Gaussian Splatting framework that formulates Gaussian densification as an attenuation-aware Markov Chain Monte Carlo (MCMC) sampling process. By interpreting Gaussians as samples from an underlying anatomical attenuation distribution, AD-GS adaptively concentrates representation capacity in high-attenuation regions, enabling sharper structural boundaries under sparse projections. To further constrain reconstruction, we incorporate a semantic regularization based on zero-shot features from Segment Anything in Medical Images, enforcing multi-view consistency through semantic priors. Experiments on the ToothFairy3 dental CBCT dataset demonstrate that AD-GS achieves superior structural fidelity and boundary preservation compared with existing…