Low-rank MERA Decomposition of 3D OCT Image Volume for Compression, Denoising, Feature Extraction and Diagnosis of Retinal Diseases

Ivica Kopriva, Fei Shi, Marija Štanfel, Qin Peng, Jianhao Bao +2

Optical coherence tomography (OCT) is a non-invasive imaging modality used for visualization of retinal tissue. However, OCT volumes are affected by speckle noise, which degrades image contrast and obscures fine structural details. Furthermore, modern clinical practice requires large field-of-view, high-resolution OCT volumes, whose storage and transmission are demanding for archiving and teleophthalmology applications. To address aforementioned challenges, we propose a low-rank multi-scale entanglement renormalization ansatz (MERA) tensor network approximation of 3D OCT image volume, where the image volume is represented as contractions of a top core factor encoding global features and multiple interacting low-rank orthogonal or semi-orthogonal factors modeling inter- and intra-B scan correlations. This representation jointly enables compression, denoising, and feature extraction. Unlike deep learning approaches, the proposed approach is training-free and processes each OCT volume independently. We evaluate the proposed framework on OCT image volumes acquired by two different scanners and demonstrate improved visual quality and reduced retinal layer segmentation errors in…