BrainCoT: A Multi-Task Zero-Shot Brain Signal Foundation Model with Neurometric-Anchored Chain-of-Thought Reasoning

Yiyu Gui, Mingzhi Chen, Guibo Luo, Yuchao Yang

Brain signals exhibit substantial multi-center heterogeneity, strong inter-subject variability, and highly diverse task settings, which makes it difficult to build models that generalize beyond a single task. While recent brain signal foundation models leverage large-scale pretraining to learn generalizable representations, they often fall short in practice because they still require target-data-specific supervised adaptation, lack multi-task zero-shot capability, and rarely provide verifiable evidence to support their predictions. In this work, we present BrainCoT, a multi-task zero-shot Brain signal foundation model with neurometric-anchored Chain-of-Thought (CoT) reasoning. BrainCoT unifies heterogeneous tasks into an instruction-driven framework so that, after pretraining, a single model can be directly applied to multiple tasks in zero-shot settings without additional adaptation. It further introduces neurometric-anchored chain-of-thought grounded in neurometric evidence for verifiable reasoning, and adopts Decision-Consistent Rationale Training to keep process learning aligned with correct predictions. Across extensive evaluations, BrainCoT achieves an average ACC of 67.41%…