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ByteTrail · AI and developer-tools intelligence
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Fields · this week
All fields2533Multimodal509AI agents474Frontier LLMs318Inference & serving226Teacher policy distillation196Medical image segmentation147Physics informed neural127Supervised & diffusion models106Forecasting time50Voice AI44Machine learned interatomic41Electrocardiogram ecg40Remote sensing40Deepfake detection37Federated learning34All 25 fields

Open problems across fields

  • Interface lock-in in multimodal spatial reasoning1 paper raises it · 1 addresses it

    Specializing a model on one spatial task (e.g., side detection) degrades performance on others (e.g., distance estimation), limiting general spatial intelligence.

    • ChronoReplay: One Answer Interface Is Not Enough for Streaming Spatial Intelligenceraises · addresses
  • Lack of benchmarks for agent harness reliability1 paper raises it · 1 addresses it

    Existing evaluations focus on model capabilities, not the reliability of the systems that deploy and manage agents.

    • Trial by Trace: Benchmarking AI Agent Harnesses for Reliability and Failure Attributionraises · addresses
  • Negative net value of agent memory systems1 paper raises it · 1 addresses it

    Memory systems often underperform naive retrieval, as their design can obscure or remove critical evidence from raw history.

    • Memory Tax: Dissecting the Net Value of Agent Memoryraises · addresses
  • Credit assignment in diffusion language models1 paper raises it · 2 address it

    Iterative denoising in DLMs makes it hard to attribute rewards to individual tokens, limiting reinforcement learning effectiveness.

    • DTCA: Denoising Token Credit Assignment for Reinforcement Learning in Diffusion Language Modelsraises · addresses
    • Multiscale Policy Optimization for Long-Horizon LLM Agentsaddresses
  • Uncertainty quantification failure under class imbalance1 paper raises it · 1 addresses it

    Standard uncertainty measures fail to reflect clinical ambiguity in imbalanced datasets, systematically penalizing minority classes.

    • When uncertainty quantification fails: structural vulnerabilities and corrections for selective prediction under clinical class imbalanceraises · addresses

Named by an AI from these papers' abstracts.

Rising research topics

  • AI tutors20+100.0%
  • Channel state information15+25.0%
  • Character recognition OCR12+20.0%
  • Electrocardiogram ecg40−2.4%
  • Supervised & diffusion models106−8.6%
  • Stochastic gradient descent31−11.4%
  • Physics informed neural127−14.2%
  • Machine learned interatomic41−19.6%

Papers

  • arXiv cs.AIOct 10

    WorkBorne: Discovering Agentic Tasks from Real-World Artifact Transitions

    Junyi Zhou, Yufei Wang, Qiyuan Zhang, Chuhan Wu, Zhengxi Li +5

    Developing terminal-based agents for long-horizon execution demands synthetic tasks that tightly couple complex instructions with authentic, interactive environments. However, current automated synthesis suffers from a fundamental asymmetry: instruction-oriented methods fabricate low-fidelity, synthetic environments, whereas resource-oriented methods treat real artifacts merely as static inputs, degrading task instructions into shallow, trivial operations. To address this limitation, we introduce WorkBorne, a synthesis framework that uses artifact transitions as the central primitive for modeling the full life-cycle of agentic tasks. In WorkBorne, each transition specifies who performs the task, which artifacts anchor the initial state and intended outcome, and the corresponding relationship between them. Specifically, WorkBorne first constructs coherent and diverse artifact corpora from iterative web retrieval, then discovers non-trivial transitions by identifying meaningful input-output artifact assemblies and the relations that connect them. Each discovered transition is finally instantiated into grounded agentic tasks. We construct 1,061 artifact corpora and 7,882 task…

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  • arXiv cs.AIOct 10

    Bridging Risk Approximation Gaps in Model Predictive Task Sampling via In-Context Modeling

    Jiarong Wen, Qi Tao, Kaiyu Zhang, Yun Qu, Lizhou Cai +3

    Reinforcement learning (RL) is essential for adaptive decision-making, e.g., robust Meta-RL and domain randomization (DR), and efficient post-training of large language models (LLMs), where tasks are commonly structured as Markov decision processes or prompts. A central bottleneck in all these settings is the cost of agent-environment interactions required for task selection and policy optimization. Model predictive task sampling (MPTS) has emerged as a promising approach to improve sample efficiency by querying informative tasks via a risk predictive model (RPM) trained on optimization history. However, existing RPMs suffer from two failure modes: (i) sparse optimization histories, which limit RPMs' generalization across the task space, and (ii) a one-step lag in risk approximation, which causes biased difficulty estimation as the policy evolves. This work formalizes these failure modes, derives lagged-risk decompositions that expose the resulting temporal bias, and recasts risk prediction as an in-context sequence modeling problem. The developed RPM integrates a one-step look-ahead mechanism with a temporal-weighted sliding window to mitigate data non-stationarity and scarcity,…

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  • arXiv cs.AIOct 10▲ 2

    Probable but Not Valid: A Psychometric Audit of Decision Models as Synthetic Survey Respondents

    Mantas Lukauskas, Viktorija Šarkauskaitė

    Language models are increasingly used to create synthetic survey samples, also called silicon samples. Decision models are a new class of language models that return a probability for each point of a rating scale instead of text. We ask whether these models, or the newest generative LLMs, can stand in for human respondents on a psychometric survey. We test fourteen decision models from eleven providers and 47 generative LLMs on an open Lithuanian organisational-psychology survey (n=263, 68 items), with 100 real respondent profiles, the Psychometric Similarity Score (PSS) and statistical baselines. The best generative model, MiniMax M3, reaches PSS 0.813. This is level with a Gaussian copula fit only on other respondents (0.824) and below a copula fit in sample (0.927). A second sample of 100 real people scores below the best models, so at this size PSS cannot rank them against real respondents. In 5 of 10 product lines the newest generative release scores below an earlier release of the same line beyond resampling noise, and none gains beyond it. With the default rounded readout, 13 of 14 decision models score below the generative reference gpt-5.4-mini. Of the 47 generative…

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  • arXiv cs.ROOct 10

    Scalable Multi-Human Cooperative Manipulation via Commander-Executor Coordination

    Buzhen Huang, Xingchen Wu, Yuanwang Yang, Chenyi Xie, Kun Li

    Multi-human cooperative object manipulation is a highly challenging topic in humanoid control. While existing methods can handle simple collaborative carrying tasks, they struggle with role-dependent, long-horizon, and sequential cooperative manipulation. To address this issue, we propose a hierarchical commander-executor framework that enables multiple agents to accomplish complex collaborative tasks in distinct ways. Specifically, a commander combines instructions and scene information for joint semantic and geometric planning. It then decomposes the task into role-specific subtasks and generates shared object-centric coordination plans, specifying execution timing, target positions, and manipulation actions for each agent. Conditioned on the commander's high-level strategy and each agent's local observations, the executor learns a low-level physics-based policy through a solo-to-cooperative curriculum to realize coordinated human-object interactions. The planned object trajectory provides a shared coordination target, while root positions and grasping instructions specify role-dependent execution cues. We evaluate our method on a variety of object manipulation tasks,…

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  • arXiv stat.MLOct 10

    Minimum Volume Optimal Transport for Multivariate Conformal Prediction

    Chuchen Zhang, Haojie Ren, Zhaojun Wang, Yajie Bao, Changliang Zou

    Optimal transport (OT) enables multivariate conformal prediction (CP) to construct flexible prediction sets that reflect the underlying complex distributional geometry while retaining distribution-free coverage guarantees. Existing OT-based methods typically rely on a fixed Euclidean transport cost, which can be suboptimal in terms of the volume of prediction sets. We propose Minimum-Volume OTCP, a framework that learns a Mahalanobis ground cost to directly minimize prediction-region volume over a class of positive-definite metrics. Using a metric Brenier representation, we derive a volume-based objective that depends explicitly on the Mahalanobis cost matrix and optimize it jointly with the transport map. We establish finite-sample marginal coverage of the output prediction sets and optimality of volume metrics. We further develop an individualized extension that learns covariate-dependent transport metrics, adapting the shape and orientation of prediction sets to heterogeneous conditional distributions. For this extension, we also show the asymptotic conditional coverage of our method. Simulations and real-data experiments demonstrate substantial reductions in prediction-set…

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  • arXiv cs.LGOct 10

    Prediction with Expert Advice under Heavy-Tailed Losses

    Yuki Shibukawa, Shinji Ito

    We study prediction with expert advice over $T$ rounds with $K$ experts under heavy-tailed losses whose $(1+ε)$-moment is bounded by $θ>0$ for some $ε\in(0,1]$. In this setting, existing algorithms designed for the case $ε=1$ can be suboptimal when $ε<1$, suffering an additional polynomial dependence on $K$. We characterize the minimax pseudo-regret rate as $Θ((θT)^{\frac{1}{1+ε}}(\log K)^{\fracε{1+ε}})$ and establish gap-dependent lower bounds in a self-bounded environment. To attain this minimax rate without prior knowledge of either $ε$ or $θ$, we propose Adaptive Heavy-Tailed FTRL, which uses robust data-dependent scale adaptation together with truncation. We further develop Adaptive Heavy-Tailed OMD, which likewise requires neither $ε$ nor $θ$ and achieves near-optimal regret guarantees in both adversarial and self-bounded environments. Finally, when $ε$ and $θ$ are known, an FTRL algorithm with Shannon-entropy regularization achieves optimal regret guarantees in both environments.

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  • arXiv cs.CLOct 10

    TeachGrade: Training-Free Short Answer Scoring with Teacher Evidence

    Jinhao Yan, Zhihong Shen, Shengjie Wang, Yiting Ren, Wentao Zhang +2

    Multi-subject, multi-step scoring requires consistent partial credit across grading conventions. We introduce TeachGrade, a training-free framework using teacher-graded examples. The Task Adapt module builds two frozen memories: Skill captures contextual teacher preferences beyond the rubric; CaseBank supplies local evidence. PreJudge provides retrieval cues; FinalJudge regrades the answer without preliminary scores. On 3,829 SAS-Bench answers across 12 tasks, official macro collaborative consistency score (CCS) rises from Native's 67.99 to 81.32 (+13.33 points), and pooled step exact match from 54.85% to 62.71%. Macro quadratic weighted kappa (QWK) reaches 84.71, exceeding Native, OpenJudge, ProofGrader, and Trojsten by 9.52, 3.50, 11.37, and 17.43 points, respectively, and leading on 8 tasks. Local Qwen3.8-27B gains 8.83 CCS and 4.08 QWK points, improving CCS on all 12 tasks. QWK gains over Native span 6.38--14.65 points on Portuguese automatic essay scoring (AES) and 2.16--2.24 on ASAP-SAS across label views, with lower mean absolute error. These results support reuse across languages, response formats, and backbones without weight updates.

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  • arXiv physics.comp-phOct 10

    FDTD Model of Noise Pollution from an AI Data Center

    Gavin Buxton

    The sudden growth in AI data centers is raising numerous environmental concerns. Low-frequency noise pollution is a concern for local residents, that may not just be an annoyance but also carry significant health impacts. An FDTD model of sound propagation over the topography near an AI data center is presented. The topography plays a large role in the level of noise pollution, with areas of sudden elevation on either side of the river near the AI data center more susceptible to high noise levels, while areas further afield largely protected from noise pollution by the topography. Understanding the role that topography plays in noise pollution, and capturing the noise pollution in specific topographies, can help identify areas where noise mitigation strategies might be best employed.

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  • arXiv cs.LGOct 10

    Pro-t-VAE: Closed-Form Student's t Mixtures for Robust Prototype Discovery

    Zhikang Xu, Jiarui Xing, Jian Wang

    We present a robust deep generative framework for unsupervised image prototype discovery, built on a heavy-tailed Student's t mixture prior, that bridges statistical robustness and mathematical tractability. Existing generative approaches typically rely on noise-prone Gaussian priors or computationally intensive diffusion models; neither simultaneously provides explicit latent structure nor exact analytic optimization. While diffusion models can yield strong priors, iterative sampling and intractable likelihoods limit scalability and interpretability for prototype discovery. We address these issues by constructing a Student's t latent space via a Bayesian scale-mixture formulation. This yields a fully closed-form augmented ELBO for unsupervised Student's t mixture variational autoencoders, which, to our knowledge, is the first such objective applied to robust image prototype discovery, avoiding biased variational approximations and high computational costs in prior heavy-tailed or diffusion-based frameworks. Treating precision as a latent variable automatically modulates each data point's influence, downweighting outliers to learn a data-dependent measure of trust. The result is…

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  • arXiv math.CAOct 10

    Description Complexity Bounds for Analytic Approximations of Lipschitz Functions

    Artem Vozmishchev

    We study how many bits are needed to write down an elementary analytic expression that uniformly approximates a Lipschitz function. Expressions are finite trees over the basis $\{+,-,\times,÷,\exp\}$ with the variables and rational constants, and their size is $\dc(f)$, the length of the shortest description of $f$ in a fixed binary description language. For functions of one variable we prove that every $L$-Lipschitz $F:[0,1]\to[0,1]$ has an everywhere-defined approximant of accuracy $Δ$ with $\dc(f)\le C\,(L/Δ+\lg(1/Δ+2))$ for all $L,Δ>0$, by a linear spline smoothed with logistic ramps in a description language with one repetition construct. We prove a matching lower bound valid for \emph{every} description language: for $Δ\le 1/36$ and every $L>0$ some $L$-Lipschitz function needs at least $\tfrac1{16}(L/Δ+\lg(1/Δ+2))$ bits. Hence the worst-case description complexity is $Θ(L/Δ+\lg(1/Δ+2))$. For functions on $[0,1]^d$ the same method gives $Θ_d\bigl((L/Δ)^d+\lg(1/Δ+2)\bigr)$, using a tensor-product spline whose coefficients are mixed second differences and cost $O(d)$ bits each. Without the repetition construct the upper bounds carry an additional logarithmic factor, whose…

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  • arXiv cs.CLOct 10

    Agent-Guided Evidence Acquisition for Emotion-Cause Pair Extraction

    Zhuangzhuang Pan, Yan Xia, Chee Seng Chan

    Emotion-Cause Pair Extraction (ECPE) requires identifying the causes associated with emotions expressed in a conversation. Accurate extraction can depend on evidence that is not initially available, making it important to decide when further information is worth acquiring. We study agent-guided evidence acquisition for ECPE, where a student agent selectively accesses expert judgments for borderline relations on both sides of its validation-selected F1 decision boundary and revises only queried predictions. Through controlled comparisons under different information-access conditions, we examine how delegation granularity, query selection, and response integration affect prediction quality. At a nominal 10% query rate, selective fusion improves mean pair F1 by 2.64-3.88 points over the student in our main experiments, reaching 65.14 on ECF and 49.74 on MEC4 across model families. Our analysis suggests that greater access does not always translate into better cause identification. These findings motivate acquisition strategies that consider both the relevance of newly available evidence and its effect on prediction revision, providing an empirical basis for more effective and…

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  • arXiv cs.AIOct 10

    MARL-BattleGrounds: A Novel JAX-native Benchmark for Heterogeneous and Competitive Multi-agent RL

    Ulixes Tariq Hawili, Subramanian Ramamoorthy, Yoann Altmann, Ignacio Carlucho

    We present MARL-BattleGrounds (MARL-BGs), an easy-to-use JAX-native benchmark for heterogeneous and competitive multi-agent reinforcement learning (MARL), designed to be sample-efficient, computationally efficient, and researcher-centric. MARL benchmarks are typically simple and efficient, like SMAX, where winning reduces to unit micromanagement, or rich and costly, like Dota 2. MARL-BGs fills this missing middle. Its first mode, Team Deathmatch, is a simultaneous turn-based game between two teams of five heterogeneous agents. The five classes have distinct basic, passive, and ultimate abilities designed to synergize with allies and counter enemies. Our 52 hand-designed maps with diverse obstacles include a 12-map curriculum and ten held-out validation and test maps. MARL-BGs provides two canonical evaluation modes. First, eight endgame scenarios form a hard generalization challenge: each asks a team to win an unseen, nearly lost position against a strong reactive controller within 5-10 ticks. Second, a monthly round-robin tournament retrains each submission on equal compute, plays it against every member of the current "Big Nine" field, and publishes the Elo results on the…

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  • arXiv cs.CLOct 10

    Social Bias in Chinese Large Language Models under Social Media Expressions

    Mo Zhou

    Existing Chinese social-bias benchmarks for large language models largely rely on normalized or template-based expressions, leaving the influence of internet slang, emoji, and sarcasm insufficiently examined. Safety alignment may further compress conventional plausibility ratings toward the lower end of the scale. This study constructs 73 paired probes across gender, region, and occupation. Each probe contains a neutral expression, a social-media-style expression, and a reversed-identity control. The task is reframed from direct plausibility judgment to social consensus estimation. Social-media expressions are divided into stylistic packaging, which preserves semantic polarity, and sarcastic packaging, which reverses surface polarity. Six Chinese-capable large language models are evaluated through paired differences measuring identity bias, stylistic packaging, and sarcasm shift. All models show significant identity-bias effects; five show significantly negative stylistic-packaging effects; and sarcasm shifts display a clear cross-model gradient. These findings demonstrate that expression form is not a transparent carrier in bias evaluation and that lower scores under sarcasm…

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  • arXiv cs.AIOct 10

    Beyond Outcome Feedback: Trajectory-Quality-Guided Experience-based Learning

    Bingjie Zhang, Yibo Yang, Qiantong Liu, Benshuo Fu, Yi Chang +1

    Experience-based learning enables large language model (LLM) agents to improve over time by reusing knowledge from past executions. However, existing methods typically rely on final task outcomes as feedback for experience learning, overlooking the execution process and limiting their ability to evaluate and optimize experience based on trajectory quality. To address this limitation, we propose TQG-Exp, a trajectory-quality-guided experience-based learning framework that introduces process feedback. Specifically, we introduce Trajectory Quality Loss (TQL), which jointly considers task completion and process quality to provide a learning signal beyond final task outcomes. Based on this signal, we employ paired rollouts with and without retrieved experience to guide experience optimization. Representative trajectories are selected based on their outcomes and trajectory quality to extract task-level and task-type-level experiences. Meanwhile, differences in trajectory quality between the paired groups are used to estimate the contribution of retrieved experience and update its utility. The learned utility is then combined with semantic relevance to guide subsequent experience…

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  • arXiv cs.LGOct 10

    Contrastive Linearized Laplace: Loss Geometry, Valid Repairs, and Reliable Cores

    Francisco J. Sáez-Maldonado, Luis A. Ortega, Andrés R. Masegosa, Thomas D. Nielsen

    While contrastive learning is widely used to learn deterministic representations, it does not inherently provide estimates of uncertainty. Post-hoc uncertainty estimation methods, such as the Linearized Laplace approximation (LLA), offer a way to quantify uncertainty without retraining the encoder. However, we show that directly using the LLA induced distribution over the contrastive embedding does not yield reliable pointwise uncertainty estimates for downstream tasks: embedding variance alone does not reflect whether decisions such as nearest-neighbor retrieval or cluster assignment are stable. To address this limitation, we develop a post-hoc framework based on LLA that propagates encoder uncertainty through the downstream task. We characterize the curvature of contrastive objectives and introduce positive-semidefinite repairs where needed to obtain valid local Gaussian approximations without retraining the encoder. We test the proposed approach in metagenomic binning and image classification tasks. For metagenomic binning, posterior coassignment probabilities support consensus partitions and the selection of reliable cores, leading to improvements over existing baselines.…

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  • arXiv cs.CLOct 10

    Dependency Reasoning for Aspect Sentiment Quadruple Prediction

    Shima Esfandyar, Seywan Soleymanbaigi, Fardin Akhlaghian Tab, Fatemeh Daneshfar, Mourad Oussalah

    Aspect Sentiment Quadruple Prediction (ASQP) is fundamentally a relational reasoning problem: identifying aspect-opinion-category-sentiment quadruples requires modeling structured dependencies, not merely sequential co-occurrence. Existing LLM-based approaches incorporate syntactic information indirectly, via retrieval-based demonstration selection or multi-stage training, rather than as unified, single-pass generation-time context. We present DRIFT, which linearizes dependency parse trees and injects them directly into LLM prompts as explicit relational context, enabling the model to reason over aspect-opinion dependencies rather than infer them from token proximity alone. DRIFT further integrates retrieval-augmented in-context learning and a syntax-aware LLM-based adjudication mechanism that complements exact-match evaluation under span-boundary variation. On SemEval Rest15, Rest16, and ACOS, DRIFT achieves the strongest performance among compared generative ASQP methods, reaching 54.47% and 64.10% F1 on Rest15 and Rest16, with consistent gains across short- and medium-distance aspect-opinion configurations; adjudication further shows exact-match metrics systematically…

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  • arXiv cs.CVOct 10

    MORE: Learning Motion-Oriented Registers for Driving World Models and Planning

    Yingdong Gu, Haoyu Wang, Shaocheng Yan, Zhenjun Zhao, Hao Han +7

    By predicting future states, latent world models provide rich self-supervision for end-to-end driving, but often inherit dense features from pretrained visual encoders as their world-state interface. This creates a mismatch: visual pretraining produces information-rich, spatially dense features, but their adaptation for motion-conditioned world modeling and planning is deferred to downstream training. The dense grid also makes future prediction more computationally expensive as visual resolution increases. We therefore argue that video pretraining should directly learn state representations suited to downstream world modeling and planning, rather than relying on downstream training to adapt inherited visual features. We propose ***MORE***, a V-JEPA framework that learns **M**otion-**O**riented **RE**gisters during video pretraining as a shared state interface for driving world models and planning. MORE injects temporally aligned ego motion into a small set of registers and uses them as the sole context for masked patch prediction, channeling dense patch-level supervision through a compact state bottleneck. A complementary blockwise register-masking objective further shapes…

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  • arXiv cs.CVOct 10

    ScalLoc: Continuous Oblique Thermal UAV Geo-Localization with a 2D Satellite Map

    Xiaoran Zhang, Yu Liu, Jinyu Liang, Huaxin Xiao

    Cross-modal Thermal Geo-localization (TG) provides an illumination-robust positioning solution for Unmanned Aerial Vehicles (UAVs) in Global Navigation Satellite System (GNSS)-denied environments. However, existing thermal geo-localization methods mainly focus on near-nadir observations or depend on map-side elevation priors, limiting their applicability to continuous oblique thermal localization with only geo-referenced 2D satellite maps. To address this problem, we propose ScalLoc, a scale-aligned local-to-map localization framework for continuous oblique thermal UAV geo-localization. ScalLoc follows a reconstruction--refinement--anchoring--propagation design: it reconstructs local window geometry from thermal sequences, refines camera poses using track-based pose optimization, adaptively anchors each window to the satellite map, and propagates validated states to recover frame-level global trajectories. To support systematic evaluation, we construct Thermal-Oblique, a real thermal UAV sequence dataset containing 216 urban and rural day--night trajectories and 28,112 thermal frames with frame-level annotations. Extensive experiments demonstrate that ScalLoc reduces the mean…

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  • arXiv cs.AIOct 10

    WeatherBridge: Forecast-Aware Multi-Source Input Adaptation for Pretrained Weather Forecasting Models

    Mutian Xi, Xinyu Su, Xiaohui Zhong, Hao Li

    Data-driven weather forecasting models are commonly trained on ERA5, yet operational deployment must use timely initial states from physics-based numerical weather prediction (NWP) systems whose distributions differ substantially from ERA5. Direct initialization with these states can degrade autoregressive forecasts, motivating input adaptation that keeps the pretrained forecasting model unchanged. Here, we introduce WeatherBridge, a unified, source-conditioned adapter that maps heterogeneous operational NWP initial states to ERA5 reference states without updating the pretrained forecasting model. WeatherBridge predicts the structured residual corrections with a Swin-UNet and injects source embeddings across multiple spatial scales, allowing the model to capture shared atmospheric structure and source-specific discrepancies. Its training objective combines latitude-weighted ERA5 reconstruction with One-step Rollout Alignment (ORA), which backpropagates one-step forecast error through a frozen FuXi model to optimize the adapted states for both initial state fidelity and downstream forecast compatibility. We evaluate WeatherBridge using daily GFS, HRES, and CMA initializations from…

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  • arXiv cs.LGOct 10

    Blending experimental electron density information to protein-ligand interaction

    Seonghyun Park, Shuan Chen, Jun Jin Choong, Noboru Kuno, Gyubok Lee +4

    Machine learning models for protein-ligand interactions commonly rely on atomic coordinates, which are constructed by fitting molecular models to experimental electron-density maps. However, most models represent each complex as a single fitted structure, which can omit information about conformational heterogeneity, positional uncertainty, and local density support for individual atoms at binding interfaces. To fill this gap, we present CoDE, a Coordinate and Density Encoder, pre-trained on experimental density maps. We represent each binding site on a shared three-dimensional voxel grid combining atomic occupancy, experimental electron density, and its gradient magnitude. Using approximately 100K curated complexes, we pre-train a channel-wise vision transformer to jointly reconstruct masked atomic and density channels, learning a representation that integrates structural and experimental information. We evaluate the frozen encoder on two downstream tasks: (i) binding-affinity regression under leakage-controlled splits and (ii) pocket-conditioned ligand generation. Across these settings, CoDE improves over an identically pre-trained coordinate-only encoder and remains…

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